Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

July 1, 2019

Primary Completion Date

January 31, 2023

Study Completion Date

July 31, 2023

Conditions
Patent Foramen OvaleIntrapulmonary Arteriovenous Anastamosis
Interventions
DRUG

Sildenafil

50mg administration of sildenafil, one time, one hour prior to measurements.

OTHER

Placebo

50mg administration in gel-encapsulated microcrystalline cellulose one time, one hour prior to measurements.

Trial Locations (1)

97403

Cardiorespiratory and Pulmonary Physiology Lab, Eugene

All Listed Sponsors
lead

University of Oregon

OTHER

NCT03945643 - Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension? | Biotech Hunter | Biotech Hunter