Study of TVB-2640 in Subjects With Non-Alcoholic Steatohepatitis (NASH)

PHASE2CompletedINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

March 22, 2019

Primary Completion Date

October 2, 2021

Study Completion Date

October 2, 2021

Conditions
MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
Interventions
DRUG

TVB-2640 25 mg (US)

Oral dose, tablet, daily dosing

DRUG

TVB-2640 50 mg (US)

Oral dose, tablet, daily dosing

DRUG

Placebo (US)

Oral dose, tablet, daily dosing

DRUG

TVB-2640 50 mg (China)

Oral dose, tablet, daily dosing

DRUG

Placebo (China)

Oral dose, tablet, daily dosing

DRUG

TVB-2640 75 mg (US)

Oral dose, tablet, daily dosing

Trial Locations (23)

28557

Lucas Research, Morehead City

33014

Panax, Miami Lakes

75246

Texas Digestive Disease Consultants - Dallas, Dallas

76104

Texas Digestive Disease Consultant - Ft Worth, Fort Worth

77598

Texas Digestive Disease Consultants - Webster, Webster

78229

Pinnacle Clinical Research - San Antonio, San Antonio

78613

Texas Digestive Disease Consultants - Cedar Park, Cedar Park

78749

Texas Diabetes and Endocrinology - Austin, Austin

91763

Catalina Research Institute, Montclair

91911

ProSciento, Chula Vista

92037

University of California San Diego (UCSD), San Diego

95821

Clinical Trials Research, Sacramento

100069

Beijing Friendship Hospital, Capital Medical University, Beijing

Beijing YouAn Hospital, Capital Medical University, Beijing

200336

Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai

Shanghai Tongren Hospital, Shanghai JiaoTong University School of Medicine, Shanghai

210000

The Second Hospital of Nanjing, Nanjing

310015

The Affiliated Hospital of Hangzhou Normal University, Hangzhou

510080

Nanfang Hospital, Guangzhou

The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou

The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou

528000

Foshan First People's Hospital, Foshan

All Listed Sponsors
lead

Sagimet Biosciences Inc.

INDUSTRY

NCT03938246 - Study of TVB-2640 in Subjects With Non-Alcoholic Steatohepatitis (NASH) | Biotech Hunter | Biotech Hunter