Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3

PHASE3CompletedINTERVENTIONAL
Enrollment

700

Participants

Timeline

Start Date

May 24, 2019

Primary Completion Date

November 8, 2020

Study Completion Date

October 7, 2021

Conditions
Dry Eye SyndromesDry Eye
Interventions
DRUG

RGN-259

A preservative-free, sterile eye drop solution containing Thymosin beta 4 for direct instillation into each eye, four times a day (QID) for 14 days

DRUG

Placebo

It is composed of the same excipients as RGN-259 but does not contain Thymosin beta 4

Trial Locations (20)

16066

Scott & Christie and Associates, PC, Cranberry Township

24502

Piedmont Eye Center, Lynchburg

27603

Oculus Research, Inc. at the Eye Care Center, Raleigh

28150

Visual Eyes Optometric, Shelby

38119

Total Eye Care, P.A., Memphis

40206

The Eye Care Institute, Louisville

46240

Whitson Vision, Indianapolis

46290

Midwest Cornea Associates, LLC, Indianapolis

58103

Bergstrom Eye Research, LLC, Fargo

60619

Dovilan Wyatt MD, LLC, Chicago

78731

Texan Eye/Keystone Research, Austin

80907

Vision Institute, Colorado Springs

84041

Mountain View Eye Center, Layton

84403

Country Hills Eye Center, Ogden

85032

Cornea and Cataract Consultants of Arizona, Phoenix

89052

Center For Sight, Henderson

92663

Eye Research Foundation, Newport Beach

01810

Andover Eye Associates, Andover

02767

Andover Eye Associates, Raynham

02886

Andover Eye Associates, Warwick

All Listed Sponsors
lead

ReGenTree, LLC

INDUSTRY

NCT03937882 - Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 | Biotech Hunter | Biotech Hunter