1,656
Participants
Start Date
July 13, 2020
Primary Completion Date
September 29, 2022
Study Completion Date
January 13, 2025
Streamlined weekly DOT visits
Streamlined, weekly DOT clinic visits to have health worker observe medication ingestion and screen for side effects
Weekly DOT visit reminders
Weekly SMS or interactive voice response (IVR) phone call reminder for DOT clinic visits
Cost reimbursement DOT
Reimbursement of costs associated with weekly clinic visits (15,000 Ush/visit in Weeks 2-12)
99DOTS
99DOTS-based digital adherence technology to monitor and promote adherence
Weekly SAT dosing reminders/check-ins
Weekly SMS or IVR phone call dosing reminder/check-in for side effects
Cost reimbursement SAT
Reimbursement of costs associated with streamlined refill and end-of treatment clinic visits (15,000 Ush/visit in Weeks 6 and 12)
Mulago Immune Suppression Syndrome (ISS) Clinic, Kampala
Makerere University
OTHER
Johns Hopkins Bloomberg School of Public Health
OTHER
University of Colorado, Denver
OTHER
National Heart, Lung, and Blood Institute (NHLBI)
NIH
University of California, San Francisco
OTHER