NCT03934450 - Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 17, 2018

Primary Completion Date

May 1, 2019

Study Completion Date

May 1, 2019

Conditions

MalariaGlucose 6 Phosphate Dehydrogenase Deficiency

Interventions

DRUG

RPQ

The study will compare the individual enantiomers of primaquine - R- (-)-PQ, S-(+)-PQ, and Placebo along with the racemic version.

DRUG

SPQ

The study will compare the individual enantiomers of primaquine - R- (-)-PQ, S-(+)-PQ, and Placebo along with the racemic version.

DRUG

Primaquine Phosphate

The study will compare the individual enantiomers of primaquine - R- (-)-PQ, S-(+)-PQ, and Placebo along with the racemic version.

DRUG

Placebo

The study will compare the individual enantiomers of primaquine - R- (-)-PQ, S-(+)-PQ, and Placebo along with the racemic version.

Trial Locations (1)

University of Mississippi, University

All Listed Sponsors

lead

University of Mississippi, Oxford

OTHER