Alcohol, Behavior, and Brain Imaging

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 1, 2016

Primary Completion Date

May 30, 2019

Study Completion Date

May 30, 2019

Conditions
Alcohol DrinkingBinge DrinkingDrinking BehaviorSubstance-Related DisordersEthanolPhysiological Effects of DrugsCentral Nervous System Depressants
Interventions
DRUG

Ethanol

The 0.8 g/kg body weight dose of oral alcohol (190-proof ethanol) will be divided into 4 servings of 0.2 g/kg each. The 0.8 g/kg dose is equivalent to 4 standard drinks, where a standard drink is defined as one 12 oz beer, one 5 oz glass of wine, or one 1.5 oz shot of 80 proof alcohol. Women will receive a reduced dose (0.68 g/kg) to account for sex differences in total body water

OTHER

Placebo

The placebo beverage will consist of the cranberry or orange juice plus 1% alcohol added as a taste mask. All beverages will be sprayed with an alcoholic mist to provide a strong alcoholic scent.

All Listed Sponsors
lead

University of Chicago

OTHER

NCT03930446 - Alcohol, Behavior, and Brain Imaging | Biotech Hunter | Biotech Hunter