Axillary Reverse Mapping in Preventing Lymphedema in Patients with Breast Cancer Undergoing Axillary Lymph Node Dissection

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

534

Participants

Timeline

Start Date

July 29, 2019

Primary Completion Date

November 26, 2026

Study Completion Date

January 31, 2027

Conditions
Breast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III
Interventions
DRUG

Isosulfan Blue

Given SC

PROCEDURE

Axillary Lymph Node Dissection

Undergo ALND

PROCEDURE

Mapping

Undergo ARM

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (96)

10032

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York

11548

Cancer Institute at Saint Francis Hospital, East Hills

11795

Good Samaritan Hospital Medical Center, West Islip

14623

Pluta Cancer Center, Rochester

14642

University of Rochester, Rochester

15232

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh

18711

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre

18765

Geisinger South Wilkes-Barre, Wilkes-Barre

19090

Asplundh Cancer Pavilion, Willow Grove

19104

Penn Presbyterian Medical Center, Philadelphia

University of Pennsylvania/Abramson Cancer Center, Philadelphia

19107

Pennsylvania Hospital, Philadelphia

Thomas Jefferson University Hospital, Philadelphia

19713

Helen F Graham Cancer Center, Newark

19718

Christiana Care Health System-Christiana Hospital, Newark

19945

Beebe South Coastal Health Campus, Frankford

19971

Beebe Health Campus, Rehoboth Beach

21401

Anne Arundel Medical Center, Annapolis

23235

VCU Massey Cancer Center at Stony Point, Richmond

23298

Virginia Commonwealth University/Massey Cancer Center, Richmond

27157

Wake Forest University Health Sciences, Winston-Salem

27599

UNC Lineberger Comprehensive Cancer Center, Chapel Hill

30214

Piedmont Fayette Hospital, Fayetteville

32207

Baptist MD Anderson Cancer Center, Jacksonville

32610

University of Florida Health Science Center - Gainesville, Gainesville

32806

Orlando Health Cancer Institute, Orlando

33136

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami

33146

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables

33176

UM Sylvester Comprehensive Cancer Center at Kendall, Miami

33308

Holy Cross Hospital, Fort Lauderdale

33324

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation

33442

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach

40202

The James Graham Brown Cancer Center at University of Louisville, Louisville

43054

Mount Carmel New Albany Surgical Hospital, New Albany

43210

Ohio State University Comprehensive Cancer Center, Columbus

43213

Mount Carmel East Hospital, Columbus

44024

Geauga Hospital, Chardon

44060

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor

44106

Case Western Reserve University, Cleveland

44122

UHHS-Chagrin Highlands Medical Center, Beachwood

44129

University Hospitals Parma Medical Center, Parma

44130

UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights

44145

UH Seidman Cancer Center at Saint John Medical Center, Westlake

UHHS-Westlake Medical Center, Westlake

44195

Cleveland Clinic Foundation, Cleveland

44266

University Hospitals Portage Medical Center, Ravenna

44281

University Hospitals Sharon Health Center, Wadsworth

44307

Cleveland Clinic Akron General, Akron

44870

UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky

45069

University of Cincinnati Cancer Center-West Chester, West Chester

45219

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati

46526

Goshen Center for Cancer Care, Goshen

48038

Henry Ford Macomb Hospital-Clinton Township, Clinton Township

48192

Henry Ford Wyandotte Hospital, Wyandotte

48201

Wayne State University/Karmanos Cancer Institute, Detroit

48202

Henry Ford Hospital, Detroit

48322

Henry Ford West Bloomfield Hospital, West Bloomfield

48334

Weisberg Cancer Treatment Center, Farmington Hills

48706

McLaren Cancer Institute-Bay City, Bay City

53024

Aurora Cancer Care-Grafton, Grafton

53045

Ascension Southeast Wisconsin Hospital - Elmbrook Campus, Brookfield

53215

Aurora Saint Luke's Medical Center, Milwaukee

53226

Ascension Medical Group Southeast Wisconsin - Mayfair Road, Wauwatosa

53227

Aurora West Allis Medical Center, West Allis

53233

Aurora Sinai Medical Center, Milwaukee

54311

Aurora BayCare Medical Center, Green Bay

60612

Rush University Medical Center, Chicago

66160

University of Kansas Cancer Center, Kansas City

66205

University of Kansas Hospital-Westwood Cancer Center, Westwood

66211

University of Kansas Hospital-Indian Creek Campus, Overland Park

72205

University of Arkansas for Medical Sciences, Little Rock

73104

University of Oklahoma Health Sciences Center, Oklahoma City

75235

Parkland Memorial Hospital, Dallas

75390

UT Southwestern/Simmons Cancer Center-Dallas, Dallas

77030

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston

M D Anderson Cancer Center, Houston

77079

MD Anderson West Houston, Houston

77384

MD Anderson in The Woodlands, Conroe

77478

MD Anderson in Sugar Land, Sugar Land

77515

UTMB Health Angleton Danbury Campus, Angleton

77573

MD Anderson League City, League City

UTMB Cancer Center at Victory Lakes, League City

81632

Shaw Cancer Center, Edwards

90404

Saint John's Cancer Institute, Santa Monica

92093

UC San Diego Moores Cancer Center, La Jolla

94609

Alta Bates Summit Medical Center - Summit Campus, Oakland

98029

Swedish Cancer Institute-Issaquah, Issaquah

98122

Swedish Medical Center-First Hill, Seattle

94553-3156

Contra Costa Regional Medical Center, Martinez

32224-9980

Mayo Clinic in Florida, Jacksonville

60453-2699

Advocate Christ Medical Center, Oak Lawn

08103

Cooper Hospital University Medical Center, Camden

08080

Sidney Kimmel Cancer Center Washington Township, Sewell

08876

Robert Wood Johnson University Hospital Somerset, Somerville

02905

Women and Infants Hospital, Providence

77555-0565

University of Texas Medical Branch, Galveston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Alliance for Clinical Trials in Oncology

OTHER