Discovering New Genetic Markers in Adults and Children Who May Be At Risk for Hereditary Forms of Cancer

The family history ascertainment focuses on self-reported family history of first-, second-, and third-degree family members, including types of malignancies/ pre-malignant lesions and age at diagnosis.

Approximately 2-4mL of saliva may be collected in specialized Oragene DNA Self-Collection Kit tubes or buccal swab-based collection devices.

For select participants, 1-2 tubes of blood will be drawn for DNA and RNA analysis

In certain circumstances, for Memorial Sloan Kettering participants and their family members, it may be necessary to obtain a skin biopsy.