ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

July 12, 2019

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2025

Conditions
Neurological Cancer
Interventions
DRUG

ASTX727

ASTX727 is made up of the 2 study drugs cedazuridine and decitabine. Cedazuridine is believed to work by slowing down how fast decitabine is broken down by the body. Decitabine is believed to work by blocking abnormal cells or cancer cells from growing.

Trial Locations (3)

02114

RECRUITING

Massachusetts General Hospital Cancer Center, Boston

02115

RECRUITING

Brigham and Women's Hospital, Boston

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
collaborator

Astex Pharmaceuticals, Inc.

INDUSTRY

lead

Massachusetts General Hospital

OTHER