Effect of Serotonergic Stimulation on the Gut-brain Axis

NAActive, not recruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

April 24, 2019

Primary Completion Date

March 31, 2022

Study Completion Date

December 31, 2025

Conditions
HealthyIrritable Bowel Syndrome
Interventions
OTHER

serotonergic stimulation

Increase of serotonergic activity by a single oral administration of 10 mg Escitalopram, a Selective Serotonin Reuptake Inhibitor (SSRI), packed in a coloured hydroxypropylmethylcellulose capsule.

OTHER

no serotonergic stimulation

Oral administration of a placebo. The placebo will consist of a coloured hydroxypropylmethylcellulose capsule filled with microcrystalline cellulose.

Trial Locations (1)

70182

Örebro University, Region Örebro County, Örebro

All Listed Sponsors
collaborator

Region Örebro County

OTHER

lead

Örebro University, Sweden

OTHER

NCT03920410 - Effect of Serotonergic Stimulation on the Gut-brain Axis | Biotech Hunter | Biotech Hunter