Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome.

NACompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

June 2, 2020

Primary Completion Date

October 10, 2022

Study Completion Date

October 10, 2022

Conditions
Acute Chest SyndromeSickle Cell Disease
Interventions
PROCEDURE

Intervention: Combined use of a respiratory broad panel multiplex PCR and procalcitonin

The actions or procedures added by the research are the realization of a nasopharyngeal swab in the two strategies, and the PCT assay at D1, D3 and D7 in the pathogen-directed strategy

PROCEDURE

Control: usual antibiotic treatment

usual antibiotic treatment

Trial Locations (1)

75020

Service de Réanimation et USC médico-chirurgicale, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT03919266 - Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. | Biotech Hunter | Biotech Hunter