Comparison of Two Extubation Techniques in Critically Ill Adult Patients

NATerminatedINTERVENTIONAL
Enrollment

725

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

March 26, 2020

Study Completion Date

March 26, 2020

Conditions
Weaning FailureMechanical Ventilation Complication
Interventions
PROCEDURE

Positive Pressure Extubation Technique

Positive-pressure extubation is performed by only one operator. Ventilator parameters are set to pressure support ventilation mode, with an inspiratory pressure of 15 cm H2O and PEEP of 10 cm H2O. Then, the cuff is deflated, and the ETT is removed without endotracheal suction. Once the ETT is removed, a suction catheter is introduced through the mouth to suction secretions drawn to the oropharynx by the air flow from the ventilator passing between the ETT and the larynx.

PROCEDURE

Traditional Extubation Technique

Traditional extubation is performed by 2 operators. Without reconnection to the ventilator, the closed suction system catheter is introduced by one of the operators into the ETT and suctioning is initiated. The cuff is immediately deflated by the other operator, and the ETT is removed with continuous endotracheal suction during the whole procedure by the first operator.

Trial Locations (1)

1408

Hospital Santojanni, Buenos Aires

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Matías Bertozzi

UNKNOWN

collaborator

Marco Bezzi

UNKNOWN

collaborator

Borello, Silvina, M.D.

INDIV

collaborator

Daniela Castro

UNKNOWN

collaborator

Victoria Di Giorgio

UNKNOWN

collaborator

Mariana Aguirre

UNKNOWN

collaborator

Karina Miralles

UNKNOWN

collaborator

Diego Noval

UNKNOWN

collaborator

Sebastián Fredes

UNKNOWN

collaborator

Eliana Wilhelm

AMBIG

collaborator

Mauricio Zakimchuk

UNKNOWN

collaborator

Julián Buffarini Cignoli

UNKNOWN

collaborator

Mariana Bernardini

UNKNOWN

collaborator

Leticia Rey

UNKNOWN

collaborator

Valeria Pieroni

UNKNOWN

collaborator

Pablo D´Annunzio

UNKNOWN

collaborator

Gustavo Plotnikow

UNKNOWN

collaborator

Romina Prato

UNKNOWN

collaborator

Matías Lompizano

UNKNOWN

collaborator

María Guaymas

UNKNOWN

collaborator

Matías Accoce

UNKNOWN

collaborator

Javier Dorado

UNKNOWN

collaborator

Gimena Cardoso

UNKNOWN

collaborator

Patricia Torres

UNKNOWN

collaborator

Vanesa Pavlotsky

UNKNOWN

collaborator

Emiliano Navarro

AMBIG

collaborator

Eliana Markman

AMBIG

collaborator

Paula Di Nardo

UNKNOWN

collaborator

Ivonne Kunzi Steyer

UNKNOWN

collaborator

Thomsen, Carolina, M.D.

INDIV

collaborator

Cecilia Palacios

UNKNOWN

collaborator

Mariela Davies

UNKNOWN

collaborator

Mercedes Ruffo

UNKNOWN

collaborator

Victoria Leon

UNKNOWN

collaborator

Fernando Tapia

UNKNOWN

lead

Hospital Donación Francisco Santojanni

OTHER

NCT03918811 - Comparison of Two Extubation Techniques in Critically Ill Adult Patients | Biotech Hunter | Biotech Hunter