The RIPPLE AT-PLUS Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

201

Participants

Timeline

Start Date

August 16, 2022

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Atrial Tachycardia
Interventions
PROCEDURE

Catheter ablation of atrial tachycardia: Ripple Mapping guided.

Ripple Mapping is used to map the atrial tachycardia mechanism. Using the scar thresholding technique the Ripple Map is interpreted and catheter ablation directed to the site of the heart identified as putative to the arrhythmia mechanism. All ablation lesions are confirmed to have conduction block across them using Ripple Mapping. This can include lesions created at previous ablation procedures.

PROCEDURE

Catheter ablation of atrial tachycardia: Conventional mapping guided.

Conventional activation mapping is used to map the atrial tachycardia mechanism. The resultant (activation) map is interpreted and ablation directed to the site of the heart identified as putative to the arrhythmia mechanism. All ablation lesions are confirmed to have conduction block across them using conventional mapping. This can include lesions created at previous ablation procedures.

Trial Locations (3)

L14 3PE

Liverpool Heart & Chest Hospital, London

W12 0HS

Imperial College Healthcare NHS Trust, London

NE7 7DN

Freeman Hospital, The Newcastle Upon Tyne NHS Foundation Trust, Newcastle

All Listed Sponsors
collaborator

Imperial College Healthcare NHS Trust

OTHER

collaborator

Norfolk & Norwich University Hospital Trust

UNKNOWN

collaborator

Nottingham University Hospitals NHS Trust

OTHER

collaborator

University Hospitals Plymouth NHS Trust

UNKNOWN

collaborator

Blackpool Teaching Hospitals NHS Trust

UNKNOWN

collaborator

Cardiff & Vale UHB

UNKNOWN

collaborator

University Hospitals Sussex NHS Foundation Trust

UNKNOWN

lead

Liverpool Heart and Chest Hospital NHS Foundation Trust

OTHER