Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids

NACompletedINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

November 1, 2019

Primary Completion Date

May 30, 2024

Study Completion Date

March 1, 2025

Conditions
Type II Diabetes MellitusGestational Diabetes Mellitus
Interventions
OTHER

Rotating fluids protocol

"IV fluids at a rate of 100-150 ml/hr will be administered:~* For blood glucose \< 100 mg/dL or less: IV fluids with 5% dextrose~* For blood glucose between 101-140 mg/dL: IV fluids without 5% dextrose~* For blood glucose \> 140 mg/dL on two consecutive occasions: insulin infusion protocol (Study arm 2)"

OTHER

Insulin infusion protocol

"Regular insulin at 1 unit/ml AND IV fluids at a rate of 100-150 ml/hr will be administered:~* For blood glucose \< 80 mg/dL: No insulin AND IV fluids with 5% dextrose~* For blood glucose 80-100 mg/dL: Insulin at 0.5 U/hr AND IV fluids with 5% dextrose~* For blood glucose 101-140 mg/dL: Insulin at 1.0 U/hr AND IV fluids with 5% dextrose~* For blood glucose 141-180 mg/dL: Insulin at 1.5 U/hr AND IV fluids with 5% dextrose~* For blood glucose 181-220 mg/dL: Insulin at 2.0 U/hr AND IV fluid without dextrose~* For blood glucose \> 220 mg/dL: Insulin at 2.5 U/hr AND IV fluids without dextrose"

Trial Locations (2)

17822

Geisinger, Danville

18711

Geisinger Wyoming Valley, Wilkes-Barre

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Geisinger Clinic

OTHER