23
Participants
Start Date
July 9, 2019
Primary Completion Date
November 20, 2020
Study Completion Date
November 20, 2020
Iohexol renal clearance measurement
intravenous injection of Iohexol (Omnipaque 300mg) with blood sampling at 0, 120, 180 and 240 minutes (during Day 1.
microcirculation assessment through Laser Doppler associated to iontophoresis.
endothelial function evaluated following a protocol of iontophoresis of acetylcholine (during Day 1).
Cardiovascular assessment though Intima-media Thickness and Extra-media Thickness measurement
carotid ultrasound (during Day 1)
Blood sampling
37 mL of blood sample will be performed at Day 1
Urine sampling
The urinary collection will be done during the Day 1, on the first morning urination
High-resolution peripheral quantitative computed tomography (HR-pQCT)
assessment of the Body Mass Index by HR-pQCT (during the Day 1)
Dual-energy X-ray (DXA)
assessment of bone parameters by DXA (during the Day 1)
Hopital Femme Mère Enfant - Groupement Hospitalier Est, Bron
Hospices Civils de Lyon
OTHER