NCT03909412View on ClinicalTrials.gov

Carfilzomib Based Chemotherapy Mobilization for Autologous Stem Cell Transplants in Multiple Myeloma

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

October 8, 2019

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Multiple Myeloma
Interventions
DRUG

Carfilzomib

Carfilzomib will be administered over 10 minutes for the 20 mg/m2 and 27 mg/m2 dose and over 30 minutes for all higher doses.

DRUG

Cyclophosphamide

Cyclophosphamide dosed at 2gm/m2 administered over 1 hour.

DRUG

Dexamethasone

Dexamethasone 40mg IV/PO to be administered as a premedication.

DRUG

Granulocyte Colony-Stimulating Factor

On day 7 subjects will initiate high dose G-CSF injections at 14mcg/kg daily (with a cap of 1440mcg daily).

Trial Locations (1)

07601

RECRUITING

Hackensack Meridian Health - John Theurer Cancer Center, Hackensack

All Listed Sponsors
lead

Hackensack Meridian Health

OTHER