Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 1, 2019

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Recurrent Implantation Failure
Interventions
PROCEDURE

PGT-A

ovarian stimulation, oocyte aspiration, embryo culture until the blastocyst stage (day 5/6), TE biopsy, vitrification of all embryos in the blastocyst stage, PGT-A by NGS and finally embryo transfer of genetically normal embryos in cumulative frozen-thawed embryo transfer cycles

PROCEDURE

Control

ovarian stimulation, oocyte aspiration, embryo culture until the blastocyst stage, fresh embryo transfer of the morphologically best embryo on day 5/6, vitrification of supernumerary embryos and embryo transfer in cumulative frozen-thawed embryo transfer cycles if not pregnant from the fresh cycle.

Trial Locations (1)

3000

RECRUITING

UZ Leuven, Leuven

All Listed Sponsors
lead

Universitaire Ziekenhuizen KU Leuven

OTHER