The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 20, 2019

Primary Completion Date

December 20, 2022

Study Completion Date

December 20, 2022

Conditions
Coagulation; IntravascularRotational ThromboelastometryFibrinolysis; HemorrhageTranexamic AcidTotal Hip Arthroplasty
Interventions
DRUG

Tranexamic Acid

tranexamic acid will be administered intravenously after induction of anesthesia (a bolus of 10 mg/kg or maximal dose of 1g).

DRUG

Placebo

Patients in the placebo group will receive normal saline (a bolus of sodium chloride 0.9%, 0.1 mL/kg or maximal dose of 10 mL).

Trial Locations (1)

19107

Thomas Jefferson University Hospital, Philadelphia

All Listed Sponsors
lead

Thomas Jefferson University

OTHER

NCT03897621 - The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery | Biotech Hunter | Biotech Hunter