Evaluation of Dried Blood Spot for HCV RNA Testing

NACompletedINTERVENTIONAL
Enrollment

942

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

November 30, 2020

Study Completion Date

December 1, 2020

Conditions
Hepatitis C, Chronic
Interventions
DIAGNOSTIC_TEST

Abbott RealTime HCV assay from DBS

The trial intervention will consist of testing DBS, PSC and plasma samples obtained from trial participants using the centralised molecular assays for detection of HCV RNA. Results of testing DBS samples on the HCV assay will not be used to make any clinical decisions, and should not be communicated to study participants.

DIAGNOSTIC_TEST

HCV for use on the cobas® 6800/8800 Systems from PSC and DBS

The trial intervention will consist of testing DBS, PSC and plasma samples obtained from trial participants using the centralised molecular assays cobas® 6800/8800 Systems for detection of HCV RNA. Results of testing DBS samples on the HCV assay will not be used to make any clinical decisions, and should not be communicated to study participants.

DIAGNOSTIC_TEST

Aptima® HCV Quant Dx Assay from DBS

The trial intervention will consist of testing DBS, PSC and plasma samples obtained from trial participants using the centralised molecular assays Aptima® HCV Quant Dx Assay from DBS for detection of HCV RNA. Results of testing DBS samples on the HCV assay will not be used to make any clinical decisions, and should not be communicated to study participants.

DIAGNOSTIC_TEST

HCV for use on the cobas® 4800Systems from PSC and DBS

The trial intervention will consist of testing DBS, PSC and plasma samples obtained from trial participants using the centralised molecular assays cobas® 4800 for detection of HCV RNA. Results of testing DBS samples on the HCV assay will not be used to make any clinical decisions, and should not be communicated to study participants.

Trial Locations (5)

3065

St Vincent's Institute of Medical Research National Serology Reference Laboratory, Victoria Park

11527

Hellenic Scientific Society for the Study of AIDS and Sexually Transmitted Diseases, Athens

Unknown

Centre Pasteur du Cameroun, Yaoundé

National Centre for Disease Control, Tbilisi

0000

Rwanda Military Hospital, Kigali

All Listed Sponsors
collaborator

UNITAID

OTHER

lead

Foundation for Innovative New Diagnostics, Switzerland

OTHER

NCT03896087 - Evaluation of Dried Blood Spot for HCV RNA Testing | Biotech Hunter | Biotech Hunter