Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

October 10, 2020

Study Completion Date

October 10, 2020

Conditions
PediatricsAnesthesiaVasospasm
Interventions
DRUG

Papaverine

0.12 mg/mL papaverine administered as soon as the arterial catheter is placed and secured, and 0.12 mg/mL papaverine administered one hour after initial dose

DRUG

Heparin

2 units/mL heparin administered as soon as the arterial catheter is placed and secured, and 2 units/mL heparin administered one hour after initial dose

DRUG

Rescue papaverine, as needed

If the arterial catheter spasm/patency or waveform does not improve 10 minutes after the second papaverine plus heparin or heparin only dose, then the anesthesiology care team will consider treating clinically with 0.3 mg of papaverine.

Trial Locations (1)

77030

UT Health, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT03894904 - Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients | Biotech Hunter | Biotech Hunter