Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

May 10, 2019

Primary Completion Date

March 2, 2022

Study Completion Date

March 2, 2022

Conditions

Impacted Third Molar ToothPain, Acute

Interventions

DRUG

Ibuprofen

400 mg by mouth every 4 hours for 2 days after third molar extraction and then as needed for pain up to 7 days after third molar extraction

DRUG

Acetaminophen

500 mg by mouth every 4 hours for 2 days after third molar extraction and then as needed for pain up to 7 days after third molar extraction

DRUG

Placebo

By mouth

DRUG

Oxycodone

5 mg by mouth every 6 hours as needed for pain

Trial Locations (1)

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia

All Listed Sponsors

lead

University of Pennsylvania

OTHER

NCT03893175 - Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction | Biotech Hunter | Biotech Hunter