Combination Therapy of Anthracyclines for Children With Nephroblastoma

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

June 1, 2019

Primary Completion Date

December 31, 2020

Study Completion Date

June 30, 2045

Conditions
0.5-14 Year Old Children With Nephroblastoma
Interventions
DRUG

Vincristine

Dosage according to Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

DRUG

Oxytetracycline/ Cyclophosphamide

Dosage according to Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

DRUG

Liposomal doxorubicin

The dosage of Liposomal doxorubicin is half of doxorubicin dosage in Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

DRUG

Doxorubicin

Dosage according to Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

DRUG

Pharmorubicin

The dosage of pharmorubicin is 2 times of doxorubicin dosage in Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

DRUG

Pirarubicin

The dosage of pirarubicin is equal to doxorubicin dosage in Children Wilms tumor diagnosis and therapy recommendations: Wilms Tumor-2016 (WT-2016) (2-6) Chemotherapy.

Trial Locations (1)

110004

Shenjing Hospital, Shenyang

All Listed Sponsors
lead

Shengjing Hospital

OTHER