Study Comparing Modified Lee White Clotting Time Against Twenty Minute Whole Blood Clotting Test in Snakebite Victims

CompletedOBSERVATIONAL
Enrollment

230

Participants

Timeline

Start Date

May 1, 2019

Primary Completion Date

May 31, 2020

Study Completion Date

June 30, 2020

Conditions
Coagulation DefectSnake Bites
Interventions
DIAGNOSTIC_TEST

20'Whole Blood ClottingTest (WBCT)

"1ml of blood drawn from snake bite victims in clean glass test tubes of 1 cm diameter Kept undisturbed for a period of 20 minutes (measured by a stop watch). At the end of 20 minutes the tube is tilted to see if the blood has clotted or not.~If a well formed clot is not formed, the test is recorded as 'abnormal'.~If the clot seems well formed, it is further observed for a period of 30 minutes to look for dissolution of the formed clot and would be termed clot lysis. Clot lysis indicates an unstable clot."

DIAGNOSTIC_TEST

Modified Lee and White (MLW) Method Clotting Time

"The blood collected in three additional test tubes would be utilised for MLW.~The three test tubes would be kept on a rack at ambient temperature.~The blood sample would be drawn in a 5cc syringe and 1 ml would be added in the three test tubes consecutively.~The test tube would be left undisturbed for 5 minutes, after that the first tube would be tilted approximately to check for clot formation every 30 seconds while the other tubes are left undisturbed.~After the blood in the first tube has clotted, the time would be noted and the second tube would be tilted every 30 seconds and examined.~Following its clotting, the third tube would be examined. The time at which the third tube is recorded as the CT value.~Once clotted, then the sample in the all three test tube would be assessed at 20 minute and 30 min to look for breakup or lysis of the clot."

Trial Locations (1)

680005

Jubilee Mission Medical College and Research Institute, Thrissur

All Listed Sponsors
lead

Appu Suseel

OTHER

NCT03890016 - Study Comparing Modified Lee White Clotting Time Against Twenty Minute Whole Blood Clotting Test in Snakebite Victims | Biotech Hunter | Biotech Hunter