NCT03888859 - ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

December 6, 2017

Primary Completion Date

April 13, 2019

Study Completion Date

December 8, 2020

Conditions

Hepatocellular CarcinomaLiver CancerLiver NeoplasmsMetastatic Liver Cancer

Interventions

BIOLOGICAL

ET1402L1-ARTEMIS™ T cells -IV

Autologous T cells transduced with lentivirus encoding an anti-AFP (ET1402L1) -ARTEMIS™2 expression construct -intravenous (i.v.) arm

BIOLOGICAL

ET1402L1-ARTEMIS™ T cells -intra-hepatic artery

Autologous T cells transduced with lentivirus encoding an anti-AFP (ET1402L1) -ARTEMIS™2 expression construct: intra-hepatic artery (i.a.) arm

BIOLOGICAL

ET1402L1-ARTEMIS™ T cells -Intratumoral Injections

Autologous T cells transduced with lentivirus encoding an anti-AFP (ET1402L1) -ARTEMIS™2 expression construct: Intratumoral Injections (i.t.) arm

Trial Locations (1)

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an