50
Participants
Start Date
July 30, 2024
Primary Completion Date
March 31, 2027
Study Completion Date
March 31, 2027
Hemiarch repair
Current standard of surgical repair consisting of ascending aortic replacement with open distal anastomosis at level of proximal arch under a period of hypothermic circulatory arrest . No surgical or endovascular intervention is carried out in the mid arch or descending aorta. Intra-operative management, including cannulation, cardioplegia, cerebral perfusion technique, and neurologic monitoring will be done according to each institution's current standard of practice.
Extended arch repair
Surgical replacement of the ascending aorta along with intervention on the arch and descending aorta. Techniques for distal aspect of extended arch technique include but are not limited to total arch replacement along with TEVAR, Frozen Elephant Trunk procedure or surgical proximal arch replacement with bare metal stents in arch and descending aorta. Intra-operative management, including cannulation, cardioplegia, cerebral perfusion technique, and neurologic monitoring will be done according to each institution's current standard of practice.
RECRUITING
London Health Sciences Centre, London
RECRUITING
University Health Network, Toronto
RECRUITING
Montreal Heart Institute, Montreal
RECRUITING
Institut Universitaire De Cardiologie Et De Pneumologie de Québec, Québec
Ottawa Heart Institute Research Corporation
OTHER