Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)

NACompletedINTERVENTIONAL
Enrollment

317

Participants

Timeline

Start Date

March 13, 2020

Primary Completion Date

February 28, 2025

Study Completion Date

February 28, 2025

Conditions
Osteoarthritis of Knee
Interventions
BEHAVIORAL

Focused Breathing and Attention Training (BAT)

Participants will receive mindfulness-based mental training regimen to independently practice mindfulness meditation.

BEHAVIORAL

Standard Breathing and Attention Training (BAT)

Standard BAT intervention will incorporate most of the general aspects of the Focused BAT intervention but without the specific instructions related to mindfully attending to the breath in a non-evaluative manner.

DEVICE

Transcranial Direct Current Stimulation (tDCS)

A Soterix 1x1 Clinical Trials Direct Current Stimulator will apply 20 minutes of 2.0mA direct current through two bicarbon rubber electrodes encased in saline-soaked sponges

DEVICE

Sham Transcranial Direct Current Stimulation (tDCS)

Sham stimulation procedures will be identical except for the duration of stimulation. Participants will receive 30 seconds of 2 mA (30s ramp up/down) of stimulation at the beginning of the session.

Trial Locations (2)

32610

University of Florida, Gainesville

35294

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of Florida

OTHER

NCT03884374 - Pain Relief for OsteoArthritis Through Combined Treatment (PROACT) | Biotech Hunter | Biotech Hunter