Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers

NACompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

March 30, 2018

Primary Completion Date

August 30, 2019

Study Completion Date

August 30, 2019

Conditions
CO2 ClearanceMask ComfortRebreathing Exhaled Gas
Interventions
DEVICE

Evaluated 4 masks used for NIV with mechanical ventilators

Order of the masks (BiTrac MaxShield™ with standard elbow, BiTrac™ Full Face with standard elbow, Respironics PerforMax with standard elbow, and Respironics AF531 with standard elbow) were randomly chosen. Investigators randomly assigned all masks for paper raffling from container. All subjects performed 20 minutes on each mask followed by 5 minutes wash out interval between masks. EPAP levels will be 0, 2, 4, \& 5 (5 minutes for each level) while IPAP remains at 5 higher than EPAP. FiCO2 and EtCO2 were collected at 4:00, 4:30 and 5:00 minute mark for each EPAP level. Also, subjective mask comfort was assessed via visual analog scale (VAS) with 1 referring to least comfortable and 5 being the most comfortable after 5 each EPAP setting.

Trial Locations (1)

60612

Rush University Medical Center, Chicago

All Listed Sponsors
lead

Rush University Medical Center

OTHER

NCT03882723 - Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers | Biotech Hunter | Biotech Hunter