Does Sound Conditioning Protect Against Temporary Hearing Damage

CompletedOBSERVATIONAL
Enrollment

32

Participants

Timeline

Start Date

January 1, 2020

Primary Completion Date

April 1, 2020

Study Completion Date

April 1, 2020

Conditions
Hearing Loss, Noise-Induced
Interventions
DIAGNOSTIC_TEST

Session One Test Battery

"Prior to noise exposure:~Test battery - High-frequency audiometry, Distortion Product Otoacoustic Emissions, Middle Ear Muscle Reflex, Speech-in-Noise test (Around 35 minutes with breaks if required)~* Extended Frequency Audiometry (\~ 8 min), 0.25-16 kHz: Participants will be asked to press the button when they hear a sound through the headphones in a soundproof booth.~* DPOAE (\~ 5 min), 0.5-10 kHz: A small tip will be placed in participants' ear and they will hear a sound. The tip measures a response from hair cells in the cochlea and they will not need to do anything.~* MEMR (\~ 8 min), 4 kHz: A small tip placed in both ears and again a sound heard, however, this sound will gradually get louder until an involuntary muscle reflex is noted.~* Speech-in-Noise Test (\~ 5 min): Participants asked to repeat back a list of words as best as they can.~* Tinnitus: Participants were also asked if they experience any tinnitus i.e. bilateral, lasting \> 5 minutes. This was reported as Y/N."

DIAGNOSTIC_TEST

Session Two Test Battery

"Exposure at single loud music event (Important that this is part of participants' normal recreational routine, and specifically require that attendance is not prompted by participation in this study): Participants to use sound level meter provided from the Audiology Department at Charing Cross Hospital or sound level meter applications to measure sound levels inside the loud event.~Morning after exposure: Repeat test battery from session one - Ideally as soon as event is over."

DIAGNOSTIC_TEST

Session Three Test Battery

1 week later (recovery): Repeat test battery.

Trial Locations (1)

Unknown

St Mary's Hospital, London

All Listed Sponsors
lead

Imperial College Healthcare NHS Trust

OTHER

NCT03878875 - Does Sound Conditioning Protect Against Temporary Hearing Damage | Biotech Hunter | Biotech Hunter