Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast

NAActive, not recruitingINTERVENTIONAL
Enrollment

295

Participants

Timeline

Start Date

May 10, 2019

Primary Completion Date

November 14, 2029

Study Completion Date

November 14, 2034

Conditions
DCISBreast CancerLow Risk DCISBreast Conserving SurgeryRadiotherapy Omission
Interventions
RADIATION

Radiotherapy

two fractionation regimens will be allowed for whole-breast irradiation: 50 Gy in 25 fractions over 5 weeks or 40 Gy in 15 fractions over 3 weeks. The delivery of an additional dose to the tumour bed (boost) will be at the referring physician discretion, according to the guidelines

OTHER

No Radiotherapy

No Irradiation- Active surveillance

Trial Locations (37)

Unknown

Institut de Cancérologie de l'Ouest -Site Paul Papin, Angers

Institut Sainte Catherine, Avignon

Centre d'Oncologie et de Radiothérapie du Pays Basque, Bayonne

Clinique Belharra, Bayonne

Institut Bergonie, Bordeaux

Centre Francois Baclesse, Caen

Centre Hospitalier du Cotentin, Cherbourg

Centre Jean Perrin, Clermont-Ferrand

CHIC Créteil, Créteil

Hôpital Henri Mondor, Créteil

Centre Georges Francois Leclerc, Dijon

Centre Hospitalier De Lagny Sur Marne, Jossigny

CHU Saint-Pierre La Réunion, La Réunion

Centre Guillaume le Conquérant, Le Havre

Centre Oscar Lambret, Lille

Chu De Limoges - Hopital Dupuytren, Limoges

Centre Hospitalier Bretagne Sud, Lorient

Centre de Radiothérapie Mermoz, Lyon

Centre Léon Berard, Lyon

Hôpital La Croix Rousse, Lyon

Institut Regional Du Cancer Montpellier Val D Aurelle, Montpellier

Centre Azuréen De Cancérologie, Mougins

Centre Antoine Lacassagne, Nice

Centre de Haute Energie, Nice

Hopital Pitie Salpetriere, Paris

Institut CURIE, Paris

Centre Hospitalier Lyon Sud, Pierre-Bénite

Institut Jean Godinot, Reims

Centre Eugène Marquis, Rennes

Centre Frédéric Joliot, Rouen

Hôpital René Huguenin - Institut Curie, Saint-Cloud

CHU Saint-Etienne, Saint-Etienne

Centre De Radiothérapie De La Robertsau, Strasbourg

Centre Paul Strauss, Strasbourg

Institut Claudius Regaud, Toulouse

Institut De Cancerologie De Lorraine Alexis Vautrin, Vandœuvre-lès-Nancy

Gustave Roussy, Villejuif

All Listed Sponsors
collaborator

The French National Cancer Institute

UNKNOWN

lead

UNICANCER

OTHER

NCT03878342 - Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast | Biotech Hunter | Biotech Hunter