Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

June 28, 2016

Primary Completion Date

February 7, 2018

Study Completion Date

February 7, 2018

Conditions
Healthy VolunteersAmyotrophic Lateral Sclerosis
Interventions
DRUG

[18F]PBR06

Subjects will undergo PET imaging using 1 single intravenous (IV) injection of \[18F\]PBR06, a PET radioligand for evaluation of microglial activation in the brain. PBR06 will be injected intravenously as a bolus at a dose of no more than 5.5mCi (millicurie).

Trial Locations (1)

06510

Molecular NeuroImaging, LLC, New Haven

Sponsors
All Listed Sponsors
lead

Molecular NeuroImaging

OTHER