A Study of KN046 in Subjects With Locally Advanced or Metastatic Triple-negative Breast Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

May 30, 2019

Primary Completion Date

August 16, 2022

Study Completion Date

October 27, 2022

Conditions
Triple-negative Breast Cancer
Interventions
BIOLOGICAL

KN046

KN046 at a dose level of 3 or 5 mg/kg via intravenous infusion on Days 1 and 15 of 28-day cycle

DRUG

Nab-paclitaxel

Nab-paclitaxel at dose level of 100 mg/m2 via intravenous infusion on Days 1, 8 and 15 of 28-day cycle

Trial Locations (12)

Unknown

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing

The First Affiliated Hospital of Xiamen University, Xiamen

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

Sun Yat-sen University Cancer Center, Guangzhou

Harbin Medical University Cancer Hospital, Harbin

Henan Cancer Hospital, Zhengzhou

Hunan Cancer Hospital, Changsha

Nantong Tumor Hospital, Nantong

JiLin Cancer Hospital, Changchun

Liaoning Cancer Hospital, Shenyang

LiaoCheng People's Hospital, Liaocheng

Zibo Municipal Hospital, Zibo

All Listed Sponsors
lead

Jiangsu Alphamab Biopharmaceuticals Co., Ltd

INDUSTRY

NCT03872791 - A Study of KN046 in Subjects With Locally Advanced or Metastatic Triple-negative Breast Cancer | Biotech Hunter | Biotech Hunter