408
Participants
Start Date
February 19, 2019
Primary Completion Date
September 20, 2021
Study Completion Date
September 20, 2021
Vitamin C,thiamine,hydrocortisone
"Vitamin C (2g) will be diluted in 100ml 0.9%NACL and administered ivd every 6 hours for 5 days or until participant is discharged from the ICU.~Thiamine(200mg) will be diluted in 100ml 0.9%NACL and administered ivd every 12 hours for 5 days or until participant is discharged from the ICU. Hydrocortisone was administered 200 mg/d as a continuous infusion for 5 days or until participant is discharged from the ICU."
Placebo
Normal saline (0.9% NaCl solution) volume to match all components
Northern Jiangsu Province people's hospital, Yangzhou
Northern Jiangsu People's Hospital
OTHER