41
Participants
Start Date
May 9, 2016
Primary Completion Date
September 4, 2017
Study Completion Date
November 12, 2018
Placebo mouthwash
Participants received placebo mouthwash (ultrapure unflavoured water) with which they rinsed their mouth for one minute, twice a day for 7 days. Resting metabolic rate and blood pressure were measured on day eight. Additionally, blood and saliva samples were taken from all the participants. Dietary records of seven days were also collected in order to confirm the foods and portion sizes consumed, preparation methods, recipes and any brand names.
Chlorhexidine mouthwash
After using placebo and complete all the physiological measurements, participants were given a further one-week supply of antibacterial mouthwash containing 0.2% chlorhexidine (Corsodyl, GlaxoSmithKline, UK), encouraged to rinse their mouth for one minute, twice a day for 7 more days. They returned to the laboratory in 7 days to repeat all measurements in the same order.
Laboratory of Nutrition, Exercise & Health, Plymouth
University of the West of Scotland
OTHER
University of Plymouth
OTHER