20
Participants
Start Date
June 1, 2019
Primary Completion Date
January 31, 2021
Study Completion Date
March 1, 2021
blood test
13 blood samples will be drawn: at 3 min, 7 min, 15 min, 30min, 1h, 1.5h, 2h, 2.5h, 3h, 3.5h, 4h, 4.5h, and 5h post-treatment with TXA. Blood samples will be processed for ROTEM® analysis and for plasma concentration of TXA. TXA plasma concentrations will be modeled with a non-linear mixed-effects strategy using Monolix 4.1 and NONMEM(®) 7.2.
Brigham and Women's Hospital, Boston
Brigham and Women's Hospital
OTHER