Pressure Support and Positive End Expiratory Pressure During Spontaneous Breathing Trial

NACompletedINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

May 10, 2019

Primary Completion Date

June 1, 2023

Study Completion Date

June 1, 2023

Conditions
Critically Ill Adult Patients With Difficult Weaning
Interventions
PROCEDURE

Assisted strategy

Daily spontaneous breathing trial (SBT) with 7 cmH2O pressure support and 5 cmH2O positive end-expiratory pressure are performed to assess weanability. In case of success, a SBT with T-piece is performed to determine if the patients is at high risk of extubation failure. In this case and/or in the presence of risk factors, systematic non-invasive ventilation is applied after extubation.

PROCEDURE

Non assisted strategy

Daily spontaneous breathing trials (SBT) with T-piece are performed to assess weanability. In the presence of risk factors, systematic non-invasive ventilation is applied after extubation.

Trial Locations (1)

69317

Hôpital de la Croix-Rousse, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT03861117 - Pressure Support and Positive End Expiratory Pressure During Spontaneous Breathing Trial | Biotech Hunter | Biotech Hunter