Biomarker Exploration in Aging, Cognition and Neurodegeneration

PHASE3RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

May 1, 2018

Primary Completion Date

December 22, 2026

Study Completion Date

December 22, 2027

Conditions
Alzheimer DiseaseCognitive ImpairmentCognitive Decline
Interventions
RADIATION

Amyloid PET scan

Amyloid Positron Emission Tomography scan using radio tracer florbetapir-F18

DRUG

Tau PET scan using MK-6240

Tau Positron Emission Tomography scan using radio tracer MK-6240

BEHAVIORAL

Neurocognitive testing

A battery of clinical neuropsychological assessments and computerized cognitive tasks will be used to test participants' memory and cognitive abilities.

OTHER

MRI

High-resolution structural, functional, and diffusion Magnetic Resonance Imaging scans will be collected during the study.

Trial Locations (1)

92697

RECRUITING

University of California, Irvine, Irvine

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of California, Irvine

OTHER