80
Participants
Start Date
December 17, 2018
Primary Completion Date
October 1, 2019
Study Completion Date
November 29, 2019
Pre-operative Carbohydrate PreLoad drink
Pre-operative Carbohydrate PreLoad drink, 1 sachet given the night before surgery. One sachet given 2-4hours before surgery.
Oral Gabapentin pre-op
One dose of Gabapentin pre-operatively, 300mg orally.
Oral Lansoprazole pre-op
One dose of Lansoprazole pre-operatively, 30mg orally.
Intravenous Paracetamol intra-operatively
One dose of Paracetamol intra-operatively, 1gram intravenous infusion.
Intravenous Dexamethasone intra-operatively
One dose of Dexamethasone intra-operatively as an anti-emetic, 8mg intravenous.
Intravenous Ondansetron intra-operatively
One dose of Ondansetron intra-operatively as an anti-emetic, 4mg intravenous
Infiltration of surgical wounds with local anaesthetic
Infiltration of surgical wounds with local anaesthetic at the end of surgery, Bupivacaine 1-2mg/kg.
Intravenous Magnesium intra-operatively
One infusion of intravenous Magnesium Sulphate intra-operatively as an analgesic, 50mg/kg given over 30minutes.
Post-operative Gabapentin analgesia
Post-operative oral Gabapentin 300mg, three times daily as an analgesic.
Post-operative oral Paracetamol analgesia
Post-operative Paracetamol as an analgesic. Initially intravenously, then orally. One gram four times daily.
Post-operative Ondansetron anti-emesis
Intravenous Ondansetron administered post-operatively as prophylactic anti-emesis. 4mg three times daily, for 24 hours. Then as required.
Early extubation
Removal of the endotracheal tube in the Intensive Care Unit as soon as is safe.
Early mobilisation/physiotherapy
Mobilisation (active and passive limb movements, deep breathing) with the assistance of nurse/physiotherapist to occur as soon as possible post-operatively.
Encourage early oral food intake
Patients will be encouraged to start eating as soon as possible post-operatively
RECRUITING
James Cook University Hospital, Middlesbrough
Collaborators (1)
Medela AG
INDUSTRY
James Cook University Hospital
OTHER