NCT03852888View on ClinicalTrials.gov

Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients

NACompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

November 14, 2018

Primary Completion Date

November 23, 2020

Study Completion Date

November 25, 2021

Conditions
Rheumatoid Arthritis
Interventions
BIOLOGICAL

Urine samples taken to measure methotrexate and its major metabolite 7-OH-methotrexate level

Each patient will have to complete a total of 8 urine samples after treatment with methotrexate. The 8 samples will be taken over one week (just before taking, then 2 hours after taking treatment and then on D3, D4, D5, D6, D7, D8 before the new dose of methotrexate).

Trial Locations (1)

51092

Chu Reims, Reims

All Listed Sponsors
lead

CHU de Reims

OTHER

NCT03852888 - Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients | Biotech Hunter | Biotech Hunter