14
Participants
Start Date
May 24, 2019
Primary Completion Date
May 5, 2021
Study Completion Date
May 5, 2021
Gemtuzumab Ozogamicin 3 mg/m^2
"GO 3 mg/m\^2 on Day 1, 4, and 7~Maintenance: 2mg/m2 intravenous administration on day 1, in a 28-day cycle."
Gemtuzumab Ozogamicin 2 mg/m^2
GO 2 mg/m\^2 on Day 1 of a 28-day cycle.
Pracinostat - 45 mg
Induction: 45mg administered orally 3 days a week with 48 hours between dosing (e.g., Monday, Wednesday, and Friday) for three consecutive weeks, followed by 1 week of rest, in 28-day cycles.
Pracinostat - 60 mg
Escalation: 60 mg administered orally three days a week with 48 hours between dosing (e.g., Monday, Wednesday, and Friday) for three consecutive weeks, followed by one week of rest, in 28-day cycles.
Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Medical College of Wisconsin
OTHER