Understanding Mechanisms of Normal and Disordered Defecation

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

January 29, 2019

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Constipation
Interventions
DIAGNOSTIC_TEST

Rectal Barostat Study

Contractions will be recorded with a balloon inserted into the rectum and inflated

DIAGNOSTIC_TEST

Fecoflowmetry

Rectum will be filled with a small amount of paste.Two thin catheters will be inserted into the anus to measure pressures and electrical activity (electromyography or EMG). Subjects will be asked to sit on a commode, contract (squeeze) your anal muscles, blow into a balloon, and expel the paste into the commode.

Trial Locations (1)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Mayo Clinic

OTHER