Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements

PHASE4CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

September 24, 2019

Primary Completion Date

October 20, 2023

Study Completion Date

October 20, 2023

Conditions
Rapid Sequence Intubation
Interventions
DEVICE

Non-rebreather mask (NRBM)

The non-rebreather mask (NRBM) will be used to assist in the delivery of oxygen. Participants will be placed on NRBM at different flow rates (15 LPM, 35 LPM, or Flush rate at 55 LPM).

DEVICE

Non-invasive ventilator mask (NIV)

The NIV is a non-invasive face (nasal) mask for oxygen delivery. Participants will receive oxygen at 40% FiO2 for 3 minutes, 70% FiO2 for 3 minutes or 100% FiO2 for 3 minutes each.

DEVICE

Nasal cannula EtO2 sensor

The nasal cannula EtO2 sensor will be placed on the participant's face under the mask to detect the EtO2 levels.

DRUG

Oxygen (NRBM)

Oxygen will be delivered via the NRBM. Participants will receive oxygen at different flow rates (15 LPM, 35 LPM, or flush rate at 55 LPM).

DRUG

Oxygen (NIV)

Oxygen will be delivered via the NIV mask. Participants will receive oxygen at 40% FiO2, 70% FiO2 or 100% FiO2 for 3 minutes each.

Trial Locations (2)

30303

Grady Memorial Hospital, Atlanta

30308

Emory University Hospital Midtown, Atlanta

All Listed Sponsors
lead

Emory University

OTHER

NCT03840486 - Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements | Biotech Hunter | Biotech Hunter