968
Participants
Start Date
March 1, 2019
Primary Completion Date
April 17, 2027
Study Completion Date
September 19, 2034
AG-120
250mg tablets
Placebo for AG-120
250mg tablets
AG-221
100mg tablets
Placebo for AG-221
100mg tablets
AU-Adelaide-FLINDERS, Adelaide
AU-Adelaide-RAH, Adelaide
AU-Brisbane-PAH, Brisbane
AU-Camperdown-RPA, Camperdown
AU-Canberra-CANBERRAHOSPITAL, Canberra
AU-Douglas-TOWNSVILLE, Douglas
AU-Hobart TAS-RHOBART, Hobart
AU-Launceston TAS-LAUNCESTON, Launceston
AU-Melbourne-ALFRED, Melbourne
AU-Melbourne-AUSTIN, Melbourne
AU-Melbourne-MONASH, Melbourne
AU-Melbourne-RMELBOURNE, Melbourne
AU-Melbourne-SVHM, Melbourne
AU-Perth-FSH, Perth
AU-Perth-RPH, Perth
AU-Perth-SCGH, Perth
AU-Sydney-CONCORD, Sydney
AU-Sydney-RNSH, Sydney
AU-Sydney-SVHS, Sydney
AU-Sydney-WSAH, Sydney
AU-Waratah-CALVARYMATER, Waratah
AT-Graz-MEDUNIGRAZ, Graz
AT-Innsbruck-IMED, Innsbruck
AT-Linz-ORDENSKLINIKUM, Linz
AT-Vienna-HANUSCH, Vienna
BE-Antwerpen-ZNASTUIVENBERG, Antwerp
BE-Brugge-AZBRUGGE, Bruges
BE-Brussel-BORDET, Brussels
BE-Brussel-UZBRUSSEL, Brussels
BE-Bruxelles-STLUC, Brussels
BE-Gent-UZGENT, Ghent
BE-Haine-Saint-Paul-JOLIMONT, Haine-Saint-Paul
BE-Hasselt-VIRGAJESSE, Hasselt
BE-Leuven-UZLEUVEN, Leuven
BE-Liege-CHRCITADELLE, Liège
BE-Liege-CHULIEGE, Liège
BE-Roeselare-AZDELTA, Roeselare
BE-Yvoir-MONTGODINNE, Yvoir
EE-Tartu-TARTU, Tartu
FI-Helsinki-HUS, Helsinki
FI-Tampere-TAYS, Tampere
FR-Amiens-CHUAMIENS, Amiens
FR-Angers-CHUANGERS, Angers
FR-Argenteuil-CHARGENTEUIL, Argenteuil
FR-Bayonne-CHCOTEBASQUE, Bayonne
FR-Besançon Cedex-JEANMINJOZ, Besançon
FR-Bobigny-AVICENNE, Bobigny
FR-Chambery-CHMETROPOLESAVOIE, Chambéry
FR-Le Chesnay cedex-CHVERSAILLES, Chesnay
FR-Clamart-HIAPERCY, Clamart
FR-Clermont-Ferrand-ESTAING, Clermont-Ferrand
FR-Créteil cedex-CHUMONDOR, Créteil
FR-Grenoble cedex 9-CHUGRENOBLE, Grenoble
FR-Lens-CHLENS, Lens
FR-Lille-CHULILLE, Lille
FR-Limoges-CHULIMOGES, Limoges
FR-Lyon Pierre Benite cedex-LYONSUD, Lyon
FR-Lyon-LEONBERARD, Lyon
FR-Marseille-IPC, Marseille
FR-Montpellier-STELOI, Montpellier
FR-Mulhouse-GHRMSA, Mulhouse
FR-Nantes-CHUNANTES, Nantes
FR-Nice-CAL, Nice
FR-Nice-LARCHET, Nice
FR-Orléans-CHORLEANS, Orléans
FR-Paris cedex 10-SAINTLOUIS, Paris
FR-Paris cedex 12-SAINTANTOINE, Paris
FR-Paris cedex 15-NECKER, Paris
FR-Pessac Cedex-CHUBORDEAUX, Pessac
FR-Poitiers-CHUPOITERS, Poitiers
FR-Reims-CHREIMS, Reims
FR-Rennes cedex 9-CHURENNES, Rennes
FR-Rouen cedex-BECQUEREL, Rouen
FR-Strasbourg cedex-HAUTEPIERRE, Strasbourg
FR-Toulouse-CHUTOULOUSE, Toulouse
FR-Tours cedex-BRETONNEAU, Tours
FR-Vandoeuvre Les Nancy-CHRUNANCY, Vandœuvre-lès-Nancy
FR-Villejuif-GUSTAVEROUSSY, Villejuif
DE-Bad Saarow-HELIOSBADSAAROW, Bad Saarow
DE-Berlin-CAMPUSBENFRANKLIN, Berlin
DE-Berlin-CAMPUSVIRCHOW, Berlin
DE-Berlin-VIVANTESNEUKOLLN, Berlin
DE-Berlin-VIVANTESURBAN, Berlin
DE-Bochum-RUB, Bochum
DE-Bonn-UNIBONN, Bonn
DE-Braunschweig-KLINIKUMBRAUNSCHWEIG, Braunschweig
DE-Bremen-KBM, Bremen
DE-Dortmund-JOHODORTMUND, Dortmund
DE-Düsseldorf-MEDUNIDUESSELDORF, Düsseldorf
DE-Essen-KEM, Essen
DE-Esslingen-KLINIKUMESSLINGEN, Esslingen am Neckar
DE-Flensburg-MALTESER, Flensburg
DE-Giessen-UKGM, Giessen
DE-Goch-KKLE, Goch
DE-Hamburg-ASKLEPIOSSTGEORG, Hamburg
DE-Hamburg-ASKLEPIOS, Hamburg
DE-Hamburg-UKE, Hamburg
DE-Hamm-EVKHAMM, Hamm
DE-Hanau-KLINIKUMHANAU, Hanau
DE-Hannover-MHHANNOVER, Hanover
DE-Hannover-SILOAHKRH, Hanover
DE-Herne-MARIENHOSPITALHERNE, Herne
DE-Homburg-UNIKLINIKSAARLAND, Homburg
DE-Karlsruhe-KLINIKUMKARLSRUHE, Karlsruhe
DE-Lebach-CARITASKHLEBACH, Lebach
DE-Lemgo-KLINIKUMLIPPE, Lemgo
DE-Ludwigshafen-KLILU, Ludwigshafen
DE-Luedenscheid-KLINIKUMLUEDENSCHEID, Lüdenscheid
DE-Magdeburg-OVGU, Magdeburg
DE-Mainz-KLINKUNIMAINZ, Mainz
DE-Mainz-UNIMEDIZINMAINZ, Mainz
DE-Meschede-HOCHSAUERLAND, Meschede
DE-Minden-MUEHLENKREISKLINKEN, Minden
DE-München-IRZTUM, München
DE-München-MEDUNIMUNCHIN, München
DE-Offenburg-ORTENAUKLINIKUM, Offenburg
DE-Oldenburg-KLINIKUMOLDENBURG, Oldenburg
DE-Passau-KLINIKUMPASSAU, Passau
DE-Stuttgart-DIAKSTUTTGART, Stuttgart
DE-Stuttgart-KLINIKUMSTUTTGART, Stuttgart
DE-Traunstein-TSSOB, Traunstein
DE-Trier-MUTTERHAUS, Trier
DE-Tübingen-MEDUNITUEBINGEN, Tübingen
DE-Ulm-UNIKLINKULM, Ulm
DE-Villingen-Schwenningen-SBKVS, Villingen-Schwenningen
DE-Wuppertal-HELIOSGESUNDHEIT, Wuppertal
IE-Cork-CUH, Cork
IE-Dublin 8-STJAMES, Dublin
IE-Dublin 9-BEAUMONT, Dublin
IE-Galway-UHGALWAY, Galway
LT-Vilnius-SANTA, Vilnius
LU-Luxembourg-CHL, Luxembourg
NL-Den Bosch-JBZ, 's-Hertogenbosch
NL-Amersfoort-MEANDERMC, Amersfoort
NL-Amsterdam-AMC, Amsterdam
NL-Amsterdam-OLVG, Amsterdam
NL-Amsterdam-VUMC, Amsterdam
NL-Arnhem-RIJNSTATE, Arnhem
NL-Breda-AMPHIA, Breda
NL-Delft-RDGG, Delft
NL-Dordrecht-ASZ, Dordrecht
NL-Eindhoven-MAXIMAMC, Eindhoven
NL-Enschede-MST, Enschede
NL-Groningen-UMCG, Groningen
NL-Leeuwarden-MCL, Leeuwarden
NL-Leiden-LUMC, Leiden
NL-Maastricht-MUMC, Maastricht
NL-Nieuwegein-ANTONIUS, Nieuwegein
NL-Nijmegen-RADBOUDUMC, Nijmegen
NL-Rotterdam-ErasmusMC, Rotterdam
NL-Den Haag-HAGA, The Hague
NL-Utrecht-UMCUTRECHT, Utrecht
NL-Zwolle-ISALA, Zwolle
NO-Bergen-HELSEBERGEN, Bergen
NO-Oslo-OSLOUH, Oslo
NO-Stavanger-HELSESTAVANGER, Stavanger
NO-Tromsø-NORTHNOORWEGEN, Tromsø
NO-Trondheim-STOLAV, Trondheim
ES-Barcelona-CLINICUB, Barcelona
ES-Barcelona-GERMANTRIALS, Barcelona
ES-Barcelona-ICODURANREYNALS, Barcelona
ES-Barcelona-MUTUATERRASSA, Barcelona
ES-Barcelona-PARCDESALUTMAR, Barcelona
ES-Barcelona-SANTPAU, Barcelona
ES-Barcelona-VHEBRON, Barcelona
ES-Girona-ICSTRUETA, Girona
ES-Madrid-CSGREGORIOMARANON, Madrid
ES-Palma-SSIB, Palma
ES-Tarragona-JOAN, Tarragona
ES-Valencia-MALVARROSA, Valencia
SE-Lund-SUH, Lund
SE-Stockholm-KAROLINSKAHUDDINGE, Stockholm
SE-Uppsala-UPPSALAUH, Uppsala
CH-Basel-USB, Basel
CH-Bellinzona-IOSI, Bellinzona
CH-Bern-INSEL, Bern
CH-Fribourg-HFR, Fribourg
CH-Geneve (14)-HCUGE, Geneva
CH-Luzern-LUKS, Lucerne
CH-St. Gallen-KSSG, Sankt Gallen
CH-Zürich-USZ, Zurich
Deutsch-Österreichische Studiengruppe Akute Myeloische Leukämie (AMLSG)
UNKNOWN
Stichting Hemato-Oncologie voor Volwassenen Nederland
OTHER