Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

Taichung Veterans General Hospital ( Site 0133), Taichung

National Cheng Kung University Hospital ( Site 0134), Tainen

Auckland City Hospital ( Site 0193), Auckland

Magyar Honvedseg Egeszsegugyi Kozpont-Onkologiai Osztaly ( Site 1326), Budapest

Medizinische Universität Wien ( Site 0375), Vienna

Országos Onkológiai Intézet-Urogenital Tumors Department and Clinical Pharmacology ( Site 1325), Budapest

MHAT Serdika-Second Department of Medical Oncology ( Site 0505), Sofia

St. Vincent's Hospital ( Site 0158), Darlinghurst

Macquarie University ( Site 0151), Macquarie University

St George Hospital ( Site 0157), Kogarah

Calvary Mater Newcastle ( Site 0148), Waratah

Port Macquarie Base Hospital ( Site 0153), Port Macquarie

Tauranga Hospital ( Site 0215), Tauranga

Monash Medical Centre ( Site 0147), Clayton

MHAT Central Hospital ( Site 0503), Plovdiv

Complex Cancer Center Plovdiv-First Medical Oncology Department ( Site 0507), Plovdiv

Ordensklinikum Linz GmbH Elisabethinen ( Site 0373), Linz

Gallipoli Medical Research Ltd ( Site 0149), Greenslopes

Gold Coast University Hospital ( Site 0150), Southport

Royal Adelaide Hospital ( Site 0154), Adelaide

Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 1321), Kecskemét

Fiona Stanley Hospital ( Site 0162), Perth

Canterbury Regional Cancer & Blood Service ( Site 0195), Christchurch

Petz Aladár Megyei Oktató Kórház-Onkológiai Osztály ( Site 1324), Győr

Hospital Provincial San Pedro Alcantara ( Site 0326), Cáceres

National Taiwan University Hospital ( Site 0131), Taipei

Charite Universitaetsmedizin Berlin ( Site 0301), Berlin

National Cancer Center ( Site 0174), Goyang-si

Taipei Veterans General Hospital ( Site 0135), Taipei

Associated Medical Professionals of NY ( Site 0060), Syracuse

Seoul National University Bundang Hospital ( Site 0175), Seongnam-si

Institut Català d'Oncologia (ICO) - Girona ( Site 0321), Girona

Cherkasy Regional Oncology Dispensary ( Site 1203), Cherkassy

Istituto Clinico Humanitas Research Hospital ( Site 0452), Rozzano

Inova Schar Cancer Institute ( Site 0006), Fairfax

Virginia Cancer Institute ( Site 0052), Richmond

Universitaetsklinikum Schleswig Holstein. ( Site 0346), Lübeck

Blue Ridge Cancer Care ( Site 0086), Roanoke

CHU Jean Minjoz ( Site 0423), Besançon

Hospital Universitario Gregorio Maranon ( Site 0327), Madrid

MD Anderson Cancer Center Madrid ( Site 0332), Madrid

Hospital Clinico San Carlos ( Site 0324), Madrid

Hospital Universitario HM Sanchinarro ( Site 0322), Madrid

W. G. Bill Hefner VA Medical Center ( Site 0029), Salisbury

Hospital Quiron Madrid ( Site 0325), Madrid

Hospital Universitario Virgen de la Victoria ( Site 0337), Málaga

CHU de Brest -Site Hopital Morvan ( Site 0441), Brest

Carolina Urologic Research Center ( Site 0070), Myrtle Beach

Georgia Cancer Center at Augusta University ( Site 0026), Augusta

Institut Claudius Regaud IUCT Oncopole ( Site 0418), Toulouse

Institut Bergonie ( Site 0421), Bordeaux

Centro Di Riferimento Oncologico ( Site 0800), Aviano

Az. Osp. Univ. Sta Maria della Misericordia di Udine ( Site 0460), Udine

Moffitt Cancer Center ( Site 0080), Tampa

Institut Regional du Cancer de Montpellier - ICM ( Site 0443), Montpellier

T.C. Saglik Bakanligi Turkiye Kamu Hastaneleri Kurumu - Baki-Istanbul Bakirkoy Sadi Konuk Training ( Site 0620), Istanbul

Acıbadem Maslak Hastanesi ( Site 0660), Istanbul

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0619), Istanbul

Ege University Medicine of Faculty ( Site 0661), Bornova

University of South Alabama, Mitchell Cancer Institute ( Site 0065), Mobile

Universitaetsklinikum Goettingen ( Site 0345), Göttingen

Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Roma-Oncology Unit ( Site 0465), Verona

Ospedale Policlinico S. Orsola-Malpighi ( Site 0453), Bologna

China Medical University Hospital ( Site 0132), Taichung

Hospital Virgen del Rocio ( Site 0329), Seville

A.O. Universitaria di Modena ( Site 0454), Modena

University Hospitals Cleveland Medical Center ( Site 0036), Cleveland

Gabrail Cancer Center-Research ( Site 0096), Canton

Institut De Cancerologie De L Ouest ( Site 0448), Saint-Herblain

Centre Hospitalier Regional du Orleans ( Site 0430), Orléans

Tri-State Urologic Services PSC, Inc. ( Site 0094), Cincinnati

Instituto Valenciano de Oncologia ( Site 0331), Valencia

Methodist Hospitals. ( Site 0008), Merrillville

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori-Oncologia Medica ( Site 0464), Meldola

Universitaetsklinikum Muenster ( Site 0320), Münster

Dnepropetrovsk Regional Clinical Hospital Mechnikov-Department of urology ( Site 1205), Dnipro

Dnepropetrovsk Regional Clinical Oncology Hospital-Clinical oncological dispensary ( Site 1201), Dnipropetrovsk

Cancer & Hematology Centers of Western Michigan ( Site 0013), Grand Rapids

Munson Medical Center ( Site 0030), Traverse City

Uniklinik RWTH Aachen ( Site 0308), Aachen

Medical Oncology Ospedale San Donato ( Site 0461), Arezzo

Froedtert Hospital & the Medical College of Wisconsin ( Site 0045), Milwaukee

Centre D Oncologie de Gentilly ( Site 0432), Nancy

Krankenhaus der Barmherzigen Brueder Trier ( Site 0310), Trier

St. Vincent Frontier Cancer Center ( Site 0016), Billings

Centre Hospitalier de Valenciennes ( Site 0439), Valenciennes

Mount Sinai Hospital ( Site 0042), Chicago

CNPE Regional Center of Oncology-oncourology department ( Site 1202), Kharkiv

Centre Jean Perrin ( Site 0434), Clermont-Ferrand

Universitaetsklinikum des Saarlandes ( Site 0348), Homburg

Clinique Sainte Anne ( Site 0431), Strasbourg

Oncology Hematology West, PC dba Nebraska Cancer Specialists ( Site 0034), Omaha

C.H.U. Lyon Sud ( Site 0436), Pierre-Bénite

Tulane Cancer Center ( Site 0066), New Orleans

Yitzhak Shamir Medical Center. ( Site 0547), Ẕerifin

Universitaetsklinik fuer Urologie ( Site 0307), Tübingen

Studienpraxis Urologie ( Site 0309), Nürtingen

Institut Mutualiste Montsouris ( Site 0446), Paris

Ivano-Frankivsk Regional Hospital-Urology department ( Site 1208), Ivano-Frankivsk

"Communal Non-Commercial Enterprise Prykarpatski Clinical Oncological Center of Ivano-Frankivsk R ( Site 1209)", Ivano-Frankivsk

Universitaetsklinikum Freiburg - Medizinische Klinik ( Site 0304), Freiburg im Breisgau

CHU Amiens Picardie Site Sud Amiens ( Site 0438), Amiens

University of Colorado Cancer Center ( Site 0022), Aurora

Presidio Ospedaliero S. Maria Delle Grazie-U.O.C. ONCOLOGIA ( Site 0802), Pozzuoli

Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 0462), Napoli

Klinikum Rechts der Isar ( Site 0300), Munich

Institut Sainte Catherine ( Site 0447), Avignon

Comprehensive Cancer Centers of Nevada ( Site 0092), Las Vegas

UCLA Hematology/Oncology - Santa Monica ( Site 0081), Los Angeles

Universitaetsklinik der Paracelsus Medizinischen Privatuniversitaet ( Site 0318), Nuremberg

Hopital Foch ( Site 0428), Suresnes

Providence Medical Foundation-Oncology ( Site 0069), Fullerton

Institut Gustave Roussy ( Site 0416), Villejuif

Azienda Ospedaliera Cannizzaro ( Site 0458), Catania

Oregon Health Science University ( Site 0031), Portland

Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 1062), Bogotá

Russian Scientific Center of Roentgenoradiology ( Site 0559), Moscow

Central Clinical Hospital with Polyclinic ( Site 0562), Moscow

"State Budgetary Healthcare Institution Leningrad Regional Clinical Hospital ( Site 0588)", Gatchina

Clinical Research Center of specialized types medical care-Oncology ( Site 0570), Saint Petersburg

Russian Scientific Center of Radiology and Surgical Technologies ( Site 0567), Saint Petersburg

Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 1068), Valledupar

Oncomédica S.A.S ( Site 1057), Montería

SBHI Samara Regional Clinical Oncology Dispensary ( Site 0576), Samara

Chelyabinsk Regional Clinical Oncological Dispensary ( Site 0565), Chelyabinsk

Tomsk National Scientific Medical Center of Russian Academy of Science ( Site 0579), Tomsk

Omsk Clinical Oncology Dispensary ( Site 0568), Omsk

Krasnoyarsk Regional Clinical Oncological Dispensary ( Site 0585), Krasnoyarsk

Clínica Imbanaco S.A.S ( Site 1064), Santiago de Cali

Hemato Oncologos S.A. ( Site 1065), Santiago de Cali

HaEmek Medical Center ( Site 0548), Afula

Oncocentro ( Site 1045), Viña del Mar

National Cancer Center Hospital East ( Site 0702), Kashiwa

Rambam Health Care Campus-Oncology Division ( Site 0543), Haifa

Meir Medical Center ( Site 0544), Kfar Saba

Centro Investigación del Cáncer James Lind ( Site 1041), Temuco

Rey y Oreilly Limitada ( Site 1048), Temuco

Rabin Medical Center ( Site 0545), Petah Tikva

Chaim Sheba Medical Center ( Site 0541), Ramat Gan

Sourasky Medical Center ( Site 0542), Tel Aviv

Fundacion Arturo Lopez Perez ( Site 1049), Santiago

Assuta Ashdod Medical Center ( Site 0550), Ashdod

Pontificia Universidad Catolica de Chile ( Site 1047), Santiago

Soroka Medical Center ( Site 0549), Beersheba

Bradfordhill ( Site 1044), Santiago

Hadassah Ein Kerem Medical Center ( Site 0546), Jerusalem

Smilow Cancer Hospital at Yale New Haven ( Site 0038), New Haven

University of Massachusetts Worcester ( Site 0053), Worcester

John Theurer Cancer Center at Hackensack University Medical Center ( Site 0004), Hackensack

Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 1013), Berazategui

Organizacion Medica de Investigacion ( Site 1019), CABA

Instituto Medico Alexander Fleming ( Site 1010), Ciudad Autonoma de Buenos Aires.

Instituto de Investigaciones Clinicas ( Site 1000), Mar del Plata

Centro de Diagnostico Urologico ( Site 1008), Buenos Aires

Sanatorio Parque ( Site 1002), Rosario

Instituto de Oncologia de Rosario ( Site 1015), Rosario

Instituto de Investigaciones Metabolicas [Buenos Aires, Argentina] ( Site 1011), Buenos Aires

Hospital Aleman ( Site 1004), Buenos Aires

Centro Medico Dra De Salvo ( Site 1018), Buenos Aires

CEMAIC ( Site 1014), Córdoba

Centro Oncologico Riojano Integral ( Site 1005), La Rioja

Centro Oncologico de Integracion Regional. COIR ( Site 1007), Mendoza

Hospital Erasto Gaertner-CEPEP - Pesquisa Clínica ( Site 1036), Curitiba

Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 1032), Natal

ONCOSITE - Centro de Pesquisa Clinica em Oncologia ( Site 1038), Ijuí

Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 1021), Porto Alegre

Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 1035), Itajaí

Hospital de Base de Sao Jose de Rio Preto ( Site 1022), São José do Rio Preto

A.C. Camargo Cancer Center ( Site 1026), São Paulo

Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 1040), São Paulo

BC Cancer Victoria-Clinical Trials Unit ( Site 0111), Victoria

Health Sciences North ( Site 0122), Greater Sudbury

Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0116), Hamilton

Grand River Hospital ( Site 0120), Kitchener

Lakeridge Health ( Site 0117), Oshawa

Sunnybrook Research Institute ( Site 0108), Toronto

Princess Margaret Cancer Centre ( Site 0107), Toronto

CISSS de la Monteregie-Centre ( Site 0119), Greenfield Park

Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0106), Montreal

Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0103), Québec

CIUSSS du Bas Saint Laurent - Hopital Regional de Rimouski ( Site 0102), Rimouski

CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0105), Sherbrooke

Hospital Pablo Tobon Uribe ( Site 1066), Medellín

Biomelab S A S ( Site 1067), Barranquilla

Clinica de la Costa S.A.S. ( Site 1073), Barranquilla

Fakultni Nemocnice u sv. Anny v Brne-Onkologicko-chirurgicke oddeleni ( Site 1303), Brno

Nemocnice AGEL Novy Jicin a.s. ( Site 1304), Nový Jičín

Fakultni nemocnice Olomouc ( Site 1301), Olomouc

C.H. de Saint Quentin ( Site 0481), Saint-Quentin

Universitaetsklinikum Jena ( Site 0305), Jena

Beaumont Hospital ( Site 0726), Dublin

Tallaght University Hospital ( Site 0730), Dublin

Mid Western Cancer Centre ( Site 0728), Limerick

Azienda Ospedaliera San Camillo Forlanini ( Site 0455), Roma

Fondazione Policlinico Universitario Agostino Gemelli ( Site 0801), Roma

Azienda Ospedaliera Santa Maria Terni ( Site 0456), Terni

Toho University Sakura Medical Center ( Site 0703), Sakura

National Hospital Organization Shikoku Cancer Center ( Site 0716), Matsuyama

Iizuka Hospital ( Site 0744), Iizuka

Hakodate Goryoukaku Hospital ( Site 0739), Hakodate

Kanazawa University Hospital ( Site 0701), Kanazawa

Kitasato University Hospital ( Site 0705), Sagamihara

Yokohama City University Medical Center ( Site 0706), Yokohama

Miyagi Cancer Center ( Site 0747), Natori-shi

Nara Medical University Hospital ( Site 0715), Kashihara

Kindai University Hospital ( Site 0714), Sayama

The University of Osaka Hospital ( Site 0713), Suita

Saitama Medical University International Medical Center ( Site 0708), Hidaka

Saitama Medical Center ( Site 0743), Kawagoe

Dokkyo Medical University Saitama Medical Center ( Site 0707), Koshigaya

Hamamatsu University Hospital ( Site 0720), Hamamatsu

Yamaguchi University Hospital ( Site 0717), Ube

Chiba Cancer Center ( Site 0704), Chiba

Kyushu University Hospital ( Site 0718), Fukuoka

Hiroshima Prefectural Hospital ( Site 0748), Hiroshima

University of Miyazaki Hospital ( Site 0721), Miyazaki

Nagasaki University Hospital ( Site 0719), Nagasaki

Toranomon Hospital ( Site 0711), Tokyo

Nippon Medical School Hospital ( Site 0709), Tokyo

Keio University Hospital ( Site 0710), Tokyo

Radboud University Medical Center ( Site 0470), Nijmegen

Maastricht University Medical Centre ( Site 0467), Maastricht

Amphia Hospital Location Molengracht ( Site 0474), Breda

Catharina Ziekenhuis ( Site 0472), Eindhoven

Noordwest Ziekenhuisgroep NWZ ( Site 0468), Alkmaar

Vrije Universiteit Medisch Centrum ( Site 0479), Amsterdam

Tergooiziekenhuizen ( Site 0466), Hilversum

Spaarne Ziekenhuis ( Site 0473), Hoofddorp

Ziekenhuisgroep Twente ( Site 0469), Hengelo

Haaglanden MC - locatie Antoniushove ( Site 0471), Leidschendam

Franciscus Gasthuis en Vlietland ( Site 0489), Schiedam

Przychodnia Lekarska Komed ( Site 0628), Konin

Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 0636), Bydgoszcz

Clinical Best Solutions ( Site 0622), Warsaw

Szpital Wojewodzki im. Mikolaja Kopernika ( Site 0624), Koszalin

Salve Medica SP ( Site 0686), Lodz

Provita Prolife Centrum Medyczne ( Site 0630), Tomaszów Mazowiecki

Puerto Rico Medical Research Center LLC ( Site 1122), San Juan

FDI Clinical Research ( Site 1121), San Juan

Asan Medical Center ( Site 0176), Songpagu

Seoul National University Hospital ( Site 0171), Seoul

Samsung Medical Center ( Site 0172), Seoul

Instituto Catalan de Oncologia - ICO ( Site 0330), L'Hospitalet de Llobregat

Hospital Parc Tauli ( Site 0335), Sabadell

Hospital del Mar ( Site 0333), Barcelona

Baskent University Dr. Turgut Noyan Research and Training Center-ONCCOLOGY ( Site 0618), Adana

Ankara University Hospital Cebeci ( Site 0613), Ankara

Hacettepe Universitesi-oncology hospital ( Site 0615), Ankara

Ankara City Hospital-Medical Oncology ( Site 0616), Ankara

"LISOD - Israeli Oncological Hospital MedX-ray Internationa-Department of Clinical and Scientific ( Site 1207)", Kiev

Municipal non-profit enterprise Kyiv City Clinical Oncology -Oncourology department ( Site 1204), Kyiv

University Hospitals Bristol NHS Foundation Trust ( Site 0530), Bristol

Cambridge University Hospitals NHS Trust ( Site 0540), Cambridge

Torbay Hospital ( Site 0532), Torquay

University College London Hospitals NHS Foundation Trust ( Site 0482), London

Western General Hospital ( Site 0531), Edinburgh

Royal Marsden Hospital (Sutton) ( Site 0526), London

Musgrove Park Hospital ( Site 0537), Taunton

Mount Vernon Cancer Centre ( Site 0536), Northwood