Melatonin for Prevention of Radiation Induced Oral Mucositis

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 12, 2018

Primary Completion Date

November 9, 2018

Study Completion Date

December 1, 2018

Conditions
Oral Mucositis (Ulcerative) Due to Radiation
Interventions
DIETARY_SUPPLEMENT

Rapid Release Capsules Melatonin, 10 mg

Melatonin is a dietary supplement which is naturally produced in the body and closely involved in the natural sleep cycle. recently topical and systemic melatonin supplements. have been proposed as a new therapeutic modality for oral mucositis due to its anti-cancer, anti-inflammatory, and anti-oxidant effects.

DRUG

Miconaz oral gel

Antifungal agent

DRUG

BBC oral spray

Topical anesthetics and anti-inflammatory agent

DRUG

Oracure gel

Topical analgesic gel

OTHER

Alkamisr sachets

Sodium bicarbonate mouthwash

Trial Locations (1)

Unknown

Outpatient clinic of Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Alexandria

All Listed Sponsors
collaborator

Alexandria University

OTHER

lead

Hams Hamed Abdelrahman

OTHER

NCT03833570 - Melatonin for Prevention of Radiation Induced Oral Mucositis | Biotech Hunter | Biotech Hunter