2,570
Participants
Start Date
March 20, 2019
Primary Completion Date
June 30, 2021
Study Completion Date
June 30, 2021
Xpert MTB/RIF Ultra (Ultra)
"The intervention will consist of the WHO standard of care for children with severe pneumonia plus the study intervention consisting in rapid detection of TB on the day of hospital admission using the Ultra assay performed on 1 NPA and 1 stool sample.~The sample flow will be organised to reduce time-to-results to 3 hours. Ultra will be performed at the hospital laboratory using a standard GeneXpert device, or implemented directly inward using a one-module, battery-operated GeneXpert device (G1 Edge).~Drugs will be available at the inpatient level to enable immediate initiation of TB treatment, as soon as a positive Ultra result is available."
Kampong Cham Provincial Referral Hospital, Kampong Cham
National Pediatric Hospital, Phnom Penh
Takeo Provincial Referral Hospital, Takeo
Biyem Assi District Hospital, Yaoundé
Chantal Biya Foundation, Yaoundé
Angré University Teaching Hospital, Abidjan
Cocody University Teaching Hospital, Abidjan
Treichville University Teaching Hospital, Abidjan
Yopougon University Teaching Hospital, Abidjan
José Macamo General Hospital, Maputo
Maputo Central Hospital, Maputo
Jinja Regional Reference Hospital, Jinja
Mulago National Referral Hospital, Kampala
Holy Innocents Children's Hospital, Mbarara
Lusaka University Teaching Hospital, Lusaka
Arthur Davidson Children Hospital, Ndola
UNITAID
OTHER
Institut National de la Santé Et de la Recherche Médicale, France
OTHER_GOV