A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases

NACompletedINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

April 9, 2019

Primary Completion Date

October 26, 2023

Study Completion Date

October 26, 2023

Conditions
Metastasis to BoneRadiotherapyNeoplasm Metastasis
Interventions
RADIATION

Stereotactic body radiotherapy

Treatment will be prescribed to the periphery of the target, i.e. 80% of the dose should cover 95% of the PTV. The organ at risk (OAR) dose constraints will be in accordance with the recommendations from the report of the American Association of Physicists in Medicine (AAPM) task group 101. Image-guidance will consist of cone-beam CT in combination with 6 degrees of freedom corrections using robotic couch.

RADIATION

3D-conformal radiotherapy

In the standard setting, 95% of the PTV should receive 95% of the prescribed dose while near maximum dose (Dnear-max) in the PTV should not exceed 107%. Image-guidance will consist of portal images showing the relevant bony anatomy.

Trial Locations (1)

2610

Radiotherapy department, GZA Hospitals, Wilrijk

All Listed Sponsors
lead

Cancer Research Antwerp

OTHER

NCT03831243 - A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases | Biotech Hunter | Biotech Hunter