PD-L1 ImagiNg to prediCt Durvalumab Treatment Response in HNSCC

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

April 15, 2019

Primary Completion Date

December 17, 2020

Study Completion Date

December 9, 2021

Conditions
Head and Neck Cancer
Interventions
DIAGNOSTIC_TEST

PD-L1 imaging

89Zr-durvalumab injection followed by a PET/CT scan 5 days after injection

DRUG

Durvalumab

Durvalumab treatment is initiated after the PET/CT scan in a fixed dose of 1500 mg iv q4w

Trial Locations (4)

Unknown

Amsterdam UMC, Amsterdam

UMC Groningen, Groningen

Leiden UMC, Leiden

Radboudumc, Nijmegen

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Radboud University Medical Center

OTHER