777
Participants
Start Date
February 22, 2019
Primary Completion Date
July 29, 2020
Study Completion Date
July 29, 2020
Erenumab
70mg/1mL (70 mg) or 2x70mg/1mL (140 mg) in pre-filled syringe, administered every 4 weeks
Topiramate
"Film-coated tablet taken orally:~25 mg administered once daily (first week of titration phase). After the first week, titration was done according to the summary of product characteristics (SmPC) in 25 mg increments each week and aimed to reach the recommended daily treatment dose of 100 mg (50/75/100 mg). 50/75/100 mg were administered twice daily during titration phase and maintenance phase."
Erenumab matching placebo
Erenumab matching placebo pre-filled syringue administered every 4 weeks
Topiramate matching placebo
Topiramate matching placebo administered daily
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Lead Sponsor
Novartis Pharmaceuticals
INDUSTRY