A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

February 12, 2019

Primary Completion Date

March 8, 2019

Study Completion Date

March 15, 2019

Conditions
Drug-drug Interaction
Interventions
DRUG

Tucatinib

150mg administered orally twice daily

DRUG

Metformin

850mg administered orally

DRUG

Iohexol

1500 mg administered intravenously (IV)

Trial Locations (1)

84107

Pharmaceutical Research Associates, Salt Lake City

All Listed Sponsors
lead

Seagen Inc.

INDUSTRY

NCT03826602 - A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin | Biotech Hunter | Biotech Hunter