Transsternal Versus Transcervical Thymectomy

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 1, 1993

Primary Completion Date

December 1, 2004

Study Completion Date

December 1, 2018

Conditions
Myasthenia Gravis, Thymectomy
Interventions
PROCEDURE

Transcervical Thymectomy

Transcervical Thymectomy. All transcervical thymectomies were performed with an 8 cm transversal cervicotomy was performed approximately 2 cm above the sternal notch. Musculocutaneous flaps were developed up to the thyroid cartilage and the suprasternal notch. Strap muscles were split in the middle and retracted laterally. The upper horns of the thymus were exposed and were freed up to the level of the innominate vein. All tributary veins were suture ligated. A sternal retractor was then placed to retract the sternum upward until the patient was nearly lifted off the table. The rest of the Thymus was dissected, from the pericardium and the pleura. Care was specially taken to remove as much fatty tissue adjacent to the thymus as possible preserving the phrenic nerves.

PROCEDURE

Transsternal Thymectomy

Transsternal Thymectomy. A standard formal median sternotomy was carried out. The sternum was retracted laterally using an automatic retractor. All thymic tissue with the adjacent adipose tissue was removed starting with the inferior horns of the thymus. Thymic vessels were ligated and dissection was continued until the upper horns could be separated from the thyroid. A mediastinal tube was placed before closing the sternum and was kept in close suction for 2 to 3 days.

All Listed Sponsors
lead

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

OTHER

NCT03825185 - Transsternal Versus Transcervical Thymectomy | Biotech Hunter | Biotech Hunter